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Diez Bernal, S.; Hoby, S.; Raymond Levionnois, O.L.
Acute hyperkalaemia in a captive Persian leopard immobilised with a ketamine-medetomidine combination
2019  Veterinary Record Case Reports (7): 1-4

A 12-year-old captive male Persian leopard (Panthera pardus saxicolor) required general anaesthesia for examination and treatment of a recurrent oral fistula. Medetomidine (0.065 mg/kg) and ketamine (3.6 mg/ kg) administered intramuscularly by blowpipe darting effectively immobilised the animal that was maintained under general anaesthesia with inhaled isoflurane. In absence of clinical signs, acute hyperkalaemia (7.26 mmol/l) was incidentally recognised by the end of anaesthesia. Factors that might have played a role in hyperkalaemia development, such as the use of  2-adrenoceptor agonists, stress response, acidosis or dopamine administration, are discussed. Hyperkalaemia should be considered as a potential complication while anaesthetising large non-domestic felids.

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