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Hosseini, S.M.; Ronaghi, H.; Moshrefi, A.H.; Zaheri, B.A.; Adibi, M.A.; Tavassoli, K.
Histopathological study of gastric infection with_ Spirocerca lupi_ in Pallas's cat (_Otocolobus manul_)
2019  Comparative Clinical Pathology (28): 943-947

_Spirocerca lupi_ (family: _Spirocercidae_; order: _Spirurida_) are parasitic nematodes found in the esophagus of cats and dogs, as well as in other carnivore animals throughout the tropical, subtropical, and temperate countries of Asia and the Americas. These animals become infested by eating an intermediate host or a transport host. In adult felines, this parasite often resides in the mucosa of the esophagus, where it forms granulomatous nodules. In this work, a wild immature female Pallas's cat (_Otocolobus manul_) that was younger than 1 year old was killed by a herding dog (heeler) in Mashhad, Iran. After necropsy, parasite samples were gathered from the stomach and after clarification by lactophenol, the nematodes were recognized as _Spirocerca lupi_. Microscopic diagnoses in the stomach include granulomatous nodules, mucosal gland destruction, necrosis, and inflammatory cell infiltration. This report characterizes the first documented case of spirocercosis in a Pallas's cat in the world.

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