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Barr, M.C.; Calle, P.P.; Roelke, M.E.; Scott, F.W.
Feline immunodeficiency virus infection in nondomestic felids
1989  Journal of Zoo and Wildlife Medicine (20): 265-272

Feline immunodeficiency virus (FIV) infection has been detected by serologic methods in several species of nondomestic felids, both in captive and free-ranging populations. Antibody to FIV was detected using an enzyme-linked immunosorbent assay (ELISA) test; positive tests were confirmed by indirect immunofluorescence assay (IFA) and immunoblot procedures. Infected animals included two snow leopards (_Panthera uncia_), one lion (_P. leo_), and one jaguar (_P. onca_) from the Cheyenne Mountain Zoo, and one white tiger (_P. tigris_) and one lion from a separate facility. Six free-ranging Florida panthers (_Felis concolor coryi_) and one bobcat (_F. rufus floridanus_) from the Everglades National Park, Big Cypress National Preserve and nearby areas in southern Florida were also found to be infected. A tentative correlation between FIV seropositivity and clinical disease could be made in some of these animals; the presence of FIV infection thus may complicate the already difficult management of several endangered cat species.

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