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Larsen, R.S.; Carpenter, J.W.
Suspected vaccine- and /or dart - associated fibrosarcoma in a tiger _(Panthera tigris)_
1999 Verhandlungsbericht des.Internationalen Symposiums ber die Erkrankungen der Zoo- und Wildtiere (39): 401-404
Suspected vaccine- and/or dart-associated fibrosarcoma in a tiger (Panthera tigris) Histopathologic changes found in a grade III fibrosarcoma in a 12-yr-old captive-raised tiger (Panthera tigris) resemble those reported in vaccine-associated sarcomas in domestic cats. However, these changes are also compatible with foreign body-associated sarcomas and a broken dart needle was found near the tumor. Because the histopathologic changes are non-specific, it cannot be definitively determined whether this lesion was vaccine-induced or dart-induced; however the changes are characteristic enough to suggest that the vaccinations, the metallic foreign body, or both, contributed to this tumor's development. Because of the potential risk (albeit low) in developing sarcomas, the frequency of vaccinating exotic felids and the leaving of broken dart needles (or other foreign bodies) in exotic felids, may need to be re-evaluated.
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