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Walzer, C.; Huber, C.
Comparison of two benzodiazepine antagonists: Flumazenil and sarmazenil in the cheetah _(Acinonyx jubatus)_
1999 Verhandlungsbericht des.Internationalen Symposiums ber die Erkrankungen der Zoo- und Wildtiere (39): 377-382
This study offers a guideline for the partial antagonism of tiletamine-zolazepam (T-Z) anaesthesia in cheetahs and evaluates the possible differences between the two benzodiazepine antagonists flumazenil and sarmazenil in the species. Four cheetahs were anaesthetized 3 times at an interval of 14 days with an average i.m. dose of 4,2 mg/kg T-Z. In trials 2 and 3 Flumazenil at 31 ug/kg and Sarmazenil at 0,1 mg/kg respectively were applied i.m. 30 min after initial T-Z application. When comparing the duration and recovery from anaesthesia a highly significant difference could be established between T-Z- with and without antagonist. No significant difference could be determined between the two antagonists. The authors generally advocate caution when benzodiazepine antagonists with a novel species.
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